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Search Results for " monopolar spindle 1 "

13

Compounds

Cat No. Product Name Synonyms Targets
T3434 BAY1217389 Kinesin
BAY 1217389 is an effective and selective inhibitor of the monopolar spindle 1 (MPS1) kinase (IC50<10 nM).
T2689 AZ3146 AZ 3146 Kinesin
AZ3146 is a selective Mps1 inhibitor with IC50 of ~35 nM.
T16130 Mps1-IN-3 Kinesin
Mps1-IN-3 is an effective and selective inhibitor of MPS1 kinase (IC50: 50 nM).
T14765 BOS-172722 Kinesin
BOS-172722 is an inhibitor of monopolar spindle 1 (MPS1) checkpoint(IC50 of 2 nM).
T2313 MPI-0479605 Apoptosis , Kinesin
MPI-0479605 is an ATP competitive and selective inhibitor.
T12237 NMS-P715 Casein Kinase , Kinesin , MELK , MAPK
NMS-P715 is a selective and ATP-competitive MPS1 inhibitor(IC50 of 182 nM).
T1839 Mps1-IN-2 Kinesin , PLK
Mps1-IN-2 is a potent, selective and ATP-competitive dual Mps1/Plk1 inhibitor.
T8487 Empesertib BAY 1161909 Kinesin
Empesertib (BAY 1161909) is an orally bioavailable and selective inhibitor Mps1(IC50 < 1 nM), with potential antineoplastic activity.
T14906 CCT251455 Kinesin
CCT251455 is an inhibitor of mitotic kinase monopolar spindle 1 (MPS1; IC50: 3 nM).
T73483 RMS-07
RMS-07, a covalent inhibitor of Monopolar Spindle Kinase 1 (MPS1/TTK), exhibits a potent inhibitory concentration (IC50) of 13.1 nM. Specifically, it targets a poorly conserved cysteine located in the hinge region of the...
T17007 TC-Mps1-12 Kinesin
TC-Mps1-12 is an effective and selective inhibitor of monopolar spindle 1 (IC50: 6.4 nM) .
T73229 Mps1-IN-4
Mps1-IN-4 is a compound that selectively inhibits Monopolar spindle 1 (Mps1), exhibiting antiproliferative properties useful in cancer research.
T37050 MPS1/TTK Inhibitor MPS1/TTK Inhibitor
MPS1/TTK inhibitor is an inhibitor of monopolar spindle 1 (MPS1/TTK; IC50 = 5.8 nM), a kinase involved in mitotic spindle checkpoint signaling that is overexpressed in certain cancerous tumors. It inhibits MPS1 phosphory...
TargetMol